Aging Biology: Understanding Aging on a Molecular Level
Information
The goal of the conference is to understand the molecular mechanisms of aging at the cellular and organismal levels, and to let young investigators share and discuss cutting edge science in the field of aging biology. Through this discussion, we will propose a prescription for a healthier lifestyle by regulating aging processes and aging–related diseases.
Date
May 10, 2017 – May 12, 2017
Venue
International Conference Room
Smart Aging International Research Center, Institute of Development, Aging and Cancer, Tohoku University
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Invited Speakers [Nov. 13, 2017 Updated]
Keith Blackwell (Joslin Diabetes Center and Harvard Medical School)
Vilhelm A. Bohr (National Institute of Aging, NIH)
Judith Campisi (Buck Institute for Research on Aging)
Jan M. van Deursen (Mayo Clinic)
Eiji Hara (Osaka University)
Hisanori Horiuchi (IDAC, Tohoku University)
Shin–ichiro Imai (Washington University School of Medicine)
Fuyuki Ishikawa (Kyoto University)
Jan Hoeijmakers (Erasmus MC Rotterdam)
Hideki Katagiri (Tohoku University)
Elsa Logarinho (University of Porto)
Tom Misteli (National Cancer Institute, NIH)
Hozumi Motohashi (IDAC, Tohoku University)
Yo–ichi Nabeshima (Foundation for Biomedical Research and Innovation)
Makoto Nakanishi (University of Tokyo)
Yasuhisa Matsui (IDAC, Tohoku University)
Masashi Narita (University of Cambridge)
Emi Nishimura (Tokyo Medical and Dental University)
Toshihiko Ogura (IDAC, Tohoku University)
Yasufumi Sato (IDAC, Tohoku University)
Luis J. Sigal (Thomas Jefferson University)
Toshiyuki Takai (IDAC, Tohoku University)
Keiyo Takubo (Research Institute, National Center for Global Health and Medicine)
Kozo Tanaka (IDAC, Tohoku University)
Amy Wagers (Joslin Diabetes Center and Harvard Medical School)
Akira Yasui (IDAC, Tohoku University)
Time Schedule [Nov. 13, 2017 Updated]
- Wednesday, May 10, 2017
- Stress response and genome integrity
- 08:50 – 09:00
- Opening
- Sadayoshi Ito (Director of TFC, Tohoku University)
- Kozo Tanaka (IDAC, Tohoku University)
- Session 1: Mechanisms of Aging
- Chair: Kozo Tanaka (IDAC, Tohoku University)
- 09:00 – 09:40
- Yo–ichi Nabeshima (Foundation for Biomedical Research and Innovation)
- Alpha–Klotho in health and diseases
- 09:40 – 10:20
- Tom Misteli (National Cancer Institute, NIH)
- Nuclear architecture and aging
- 10:20 – 10:40
- Coffee Break
- Session 2: Stress Response and Aging
- Chair: Yasufumi Sato (IDAC, Tohoku University)
- 10:40 – 11:20
- Hozumi Motohashi (IDAC, Tohoku University)
- Regulation of NRF2 activity for anti–inflammation and stem cell Maintenance
- 11:20 – 12:00
- Keith Blackwell (Joslin Diabetes Center and Harvard Medical School)
- Two faces of C. elegans SKN–1 and what they tell us about Nrf1 and Nrf2
- 12:00 – 14:00
- Lunch
- Session 3: Interventions in Aging
- Chair: Hozumi Motohashi (IDAC, Tohoku University)
- 14:00 – 14:40
- Shin–ichiro Imai (Washington University School of Medicine)
- Achieving Productive Aging: The Systemic Regulatory Mechanism of Mammalian Aging and Longevity and Anti–Aging Intervention
- 14:40 – 15:20
- Masashi Narita (University of Cambridge)
- Cell–cell communication in senescence
- 15:20 – 16:00
- Jan M. van Deursen (Mayo Clinic)
- Delaying Aging and Disease by Senolysis
- 16:00 – 16:20
- Coffee Break
- Session 4: Genomic Instability in Aging
- Chair: Natsuko Chiba (IDAC, Tohoku University)
- 16:20 – 17:00
- Akira Yasui (IDAC, Tohoku University)
- Chromatin remodeling, DNA repair and transcriptional regulation in cancer and cellular aging
- 17:00 – 17:40
- Vilhelm A. Bohr (National Institute of Aging, NIH)
- DNA damage, neurodegeneration and mitochondrial dysfunction
- 17:40 – 18:20
- Jan Hoeijmakers (Erasmus MC Rotterdam)
- DNA damage, impact on aging, neurodegeneration and the effect of nutritional interventions
- Thursday, May 11, 2017
- Cell senescence and aging process of tissues
- Session 5: Cellular Senescence (1)
- Chair: Hideki Katagiri (Tohoku University)
- 09:00 – 09:40
- Makoto Nakanishi (University of Tokyo)
- Mechanisms of senescence induction and maintenance and their role in aging
- 09:40 – 10:20
- Fuyuki Ishikawa (Kyoto University)
- Cellular senescence in Post–mitotic cells
- 10:20 – 10:40
- Coffee Break
- Session 6: Cellular Senescence (2)
- Chair: Toshihiko Ogura (IDAC, Tohoku University)
- 10:40 – 11:20
- Eiji Hara (Osaka University)
- The roles and mechanisms of cellular senescence in aging and cancer
- 11:20 – 12:00
- Judith Campisi (Buck Institute for Research on Aging)
- Cellular senescence and aging phenotypes: Yin and yang
- Lunch & Poster Viewing
- 12:00 –
- Travel cost reimbursement time only for overseas speakers
- 12:00 – 13:00
- Discussion with poster presentators
- 13:00 –
- Tour to ToMMO for domestic speakers
- 14:00 –
- Tour to ToMMO for overseas speakers
- Session 7: Stem Cells and Aging
- Chair: Yasuhisa Matsui (IDAC, Tohoku University)
- 15:00 – 15:40
- Emi Nishimura (Tokyo Medical and Dental University)
- Stem cell aging: The core to orchestrates tissue aging
- 15:40 – 16:20
- Keiyo Takubo (Research Institute, National Center for Global Health and Medicine)
- Transcriptional program for hematopoietic stem cell aging
- 16:20 – 17:00
- Amy Wagers (Joslin Diabetes Center and Harvard Medical School)
- Local and systemic regulators of aging muscle stem cells
- 17:00 – 17:20
- Coffee Break
- Session 8: Immune System and Aging
- Chair: Koetsu Ogasawara (IDAC, Tohoku University)
- 17:20 – 18:00
- Toshiyuki Takai (IDAC, Tohoku University)
- Immunoreceptors Regulating Autoantibody Production in Ageing
- 18:00 – 18:40
- Luis J. Sigal (Thomas Jefferson University)
- NK cells in Aging
- 18:50 –
- Group Photo
- Friday, May 12, 2017
- Session 9: Chromosomal Changes in Aging
- Chair: Hisanori Horiuchi (IDAC, Tohoku University)
- 09:00 – 09:40
- Kozo Tanaka (IDAC, Tohoku University)
- Chromosomal instability in aging and cancer
- 09:40 – 10:20
- Elsa Logarinho (University of Porto)
- Getting older from an old mitosis
- 10:20 – 10:40
- Coffee Break
- Session 10: Organismal Aging
- Chair: Toshiyuki Takai (IDAC, Tohoku University)
- 10:40 – 11:20
- Yasufumi Sato (IDAC, Tohoku University)
- Novel link between the regulation of angiogenesis and healthy longevity
- 11:20 – 12:00
- Hisanori Horiuchi (IDAC, Tohoku University)
- A novel functional mechanism of metformin, a hypoglycemic drug with life–span extension potential
- 12:15 – 13:45
- Lunch & Meet The Experts
- Session 11: Aging–related Disorders
- Chair: Akira Yasui (IDAC, Tohoku University)
- 14:00 – 14:40
- Yasuhisa Matsui (IDAC, Tohoku University)
- Molecular bases of germ cell properties ensuring continuity of lives
- 14:40 – 15:20
- Toshihiko Ogura (IDAC, Tohoku University)
- A possibility of aging control – an approach from mechanobiology
- 15:20 – 16:00
- Hideki Katagiri (Tohoku University)
- Neuronal Information Highways for Systemic Regulation of Glucose and Energy Metabolism
- 16:00 –
- Closing Koetsu Ogasawara (IDAC, Tohoku University)
Poster
- Aging Biology: Download [PDF]
Event Registration
Closed
Contact
Registration inquiries for “Aging Science: from molecules to Society”, please contact:
Ms. Motoko Konno
Email: motoko.konno.a4*tohoku.ac.jp (change * to @)