Development and Disease
Information
Date
August 24, 2015 – August 26, 2015
Official Schedule： Mon. August 24 Tue. August 25 Wed. August 26
Venue
Auditorium of the International Center for Smart Aging Research, Seiryo Campus, Tohoku University
【#4 in the MAP】
Summary
All of the information required to generate the intricate design of our complex brains is present in the zygote after fertilization. These genetic and epigenetic programs are carefully implemented during embryonic development, during which each cell is correctly assigned its location and function as the embryo grows. Small alterations in this seemingly impossible task sometimes occur, and can have profound consequences which may ultimately result in neurodevelopmental diseases. In the second symposium, we will discuss how the program of neural development unfolds, with the aim of understanding how errors in these processes can result in the development of brain disease.
Organizers
Yasuyuki Taki
(Professor, Graduate School of Medicine / IDAC, Tohoku University)
Tomomi Shimogori
(Team Leader, RIKEN BSI)
Poster
・Download [PDF]Official Schedule
Mon. August 24
AM: Lab Tour/discussion
- 12:00 –
- Registration
- 13:00
- Welcome Ryuta Kawashima (Dean, IDAC, Tohoku University)
Session 1: Brain Development
- 13:10
- Francois Guillemot (The Francis Crick Institute, UK)
Signals and factors controlling stem cell activity in the adult brain
- 14:10
- Shubha Tole (Tata Institute of Fundamental Research, India)
Early patterning of the cortical primordium
- 14:50
-
Short talk 1
(1) Takako Kikkawa (15 min)
Dmrt genes differentially participate in Cajal-Retzius cell development of the cerebral cortex(2) Dan Ohtan Wang (15 min)
Imaging RNA in Living Neural Circuits with Hybridization-sensitive Fluorescent Probes
- 15:20
- Break
- 15:40
- Tomomi Shimogori (RIKEN BSI, Japan)
Input from the thalamus creates diversity of the cortical neurons
- 16:20
- Goichi Miyoshi (@Fishell Lab, New York University, USA)
Assembly of neocortical circuitry by FoxG1, a gene associated with neurocognitive disorders
- 16:50
- Yusuke Hirabayashi (@Polleux Lab, Columbia University, USA)
Exploring the role of the mitochondria/endoplasmic reticulum (ER) interface in axonal development
- 18:00
- Get together@Lobby of the same building
Tue. August 25
Session 2: Brain Evolution
- 9:10
- Wieland Huttner (Max Planck Institute, Dresden, Germany)
Neural stem and progenitor cells and neocortex expansion in development and evolution
- 10:10
-
Short talk 2
(1) Takuya Imamura (15 min)
Gene-activation-associated long non-coding RNAs for species-dependent epigenome formation(2) Kouta Kanno (15 min)
Individual differences of courtship ultrasonic vocalizations and its neuronal correlates in male mice
- 10:40
- Break
- 11:00
- Erich Jarvis (Duke University Medical Center, USA)
Brain evolution of complex behavioral traits: vocal learning and spoken language
- 11:40
-
Short talk 3
(1) Asuka Matsui (15 min)
Neural activity dependent BTBD3 translocation to the cytoskeleton is essential for proper dendrite development(2) Carina Hanashima (15 min)
Neuronal subtype specification in establishing the cerebral cortex
- 12:10
- Lunch & Poster session
Session 3: Models for Neurodevelopmental Disease
- 14:00
- Noboru Hiroi (Albert Einstein College of Medicine, USA)
Postnatal neurogenesis and dimensional features of autism in a genetic mouse model of 22q11.2 copy number variants
- 14:40
- Noriko Osumi (Tohoku University, Japan)
Crosstalk between Pax6 haploinsufficiency and paternal aging in modulating offspring behavior: a possible role for epigenetic modification
- 15:20
- Break
Session 4: Clinical Studies of Neurodevelopmental Disease
- 15:40
-
Short talk 4
Mikio Hoshino (30 min)
Analysis of autism susceptibility candidate 2 gene during development
- 16:10
- Stephan Sanders (UCSF, USA)
Genomic architecture and gene discovery in autism spectrum disorder
- 16:50
- Hidenori Yamasue (Tokyo University, Japan)
Crosstalk between neuroscience and clinical psychiatry with oxytocin in a neurodevelopmental disorder
- 17:30
- Reception@Lobby of the same building
Wed. August 26
- 9:30
- Yasuyuki Taki (Tohoku University, Japan)
Brain development using magnetic resonance imaging in healthy children
- 10:10
- Kenji Tsuchiya (Hamamatsu Medical University, Japan)
Neurodevelopmental Trajectories of Children with Autism Spectrum Disorder
- 10:50
- Break
- 11:10
- Atsushi Senju (Birkbeck University of London, UK)
Development of spontaneous social cognition and autism
- 12:00 – 13:10
- Lunch & Poster session
- 13:10
- Yoko Kamio (National Center of Neurology and Psychiatry, Japan)
Early detection and early intervention for ASD during life course development: Not only for social-communication problems but also for diverse mental health issues
- 13:50
- Masahiro Hirai (Jichi Medical University, Japan)
Embodied cognition from inside out in atypical development
- 14:30
- Break
- 14:50
- Paul Matthews (Imperial College London, UK)
Imaging in large populations: better defining later life brain disease risks in terms of development, exposure and aging
- 15:50
- Concluding Remarks Noriko Osumi (Tohoku University, Japan)