Future Society Design Program

Public Lecture: Space & Health


During space flight, astronauts are subjected to extreme conditions, including microgravity and high–dose cosmic radiation, which disturb the homeostasis of physiological systems within the human body. To investigate the impacts of space flight on animal health, experiments involving space mice have been conducted using the International Space Station (ISS). However, the successful live return of mice from space, or even achieving their “space travel”, has been challenging. To overcome this hurdle, the Japan Aerospace Exploration Agency (JAXA) recently established comprehensive mouse experimental system for space flight. The first missions employing this system, named Mouse Habitat Unit–1 (MHU–1), successfully launched twelve wild–type male mice, all of which returned safely to Earth after approximately a one–month stay on the ISS. One salient discovery in these missions is that ageing phenotypes, including reduced bone density and muscle mass, were significantly accelerated during space flight. Furthermore, the MHU–3 project unveiled how the deletion of Nrf2, a primary regulator of stress defense pathways, affects the health of mice staying on the ISS. The speakers will discuss future space research utilizing murine gene knockout–disease models and will provide insights to mitigate space–induced stresses that limit the further exploration of space by humans.


Sunday, November 5, 2023 13:30 – 15:00 (JST)


Kato–Kosaka Hall, Sendai Astronomical Observatory [Access]
School of Medicine Centennial Hall (Seiryo Auditorium), Seiryo Campus, Tohoku University [Access]


Sendai Astronomical Observatory: 150
Seiryo Auditorium: 50

Invited Speakers

Norishige Kanai (JAXA)
Maki Okada (JAXA)
Dai Shiba (JAXA)
Satoru Takahashi (University of Tsukuba)
Masayuki Yamamoto (Tohoku University)

Registration [Oct. 26, 2023 Updated]

Recommended for over 12 years old
Registration deadline: Sunday, October 29, 2023 12:00 (JST) November 1, 2023 12:00 (JST)
*Registration has been extended.
– Closed

Time Schedule

13:30 – 13:40
Opening and Introduction of Panelists and Facilitators
13:40 – 14:20
Introduction of the latest space research from each panelist
14:20 – 14:40
14:40 – 15:00
Q&A Session
Closing Remarks


Download [PDF]

Co–sponsored by

  • Sendai Tourism, Convention and International Association

Supported by

  • Tohoku University Tohoku Medical Megabank Organization (ToMMo)
  • Innovations in Next–Generation Medicine (INGEM)
  • Japan Aerospace Exploration Agency (JAXA)
  • Sendai Astronomical Observatory


Email: office*nrf2–vi.com (change * to @)


Event page (Japanese site)