Future Society Design Program

Environmental Stress Response and Survival Strategy of Human Being

Program Theme

Keap1–Nrf2 system plays important roles in cytoprotection on environmental stress response. By elucidating the regulatory mechanisms of Keap1–Nrf2 system, we could propose survival strategy of human being. We have been organizing a series of “The Environmental Response Symposium”, focused on the KEAP1–NRF2 system, in Japan once every few years. It has been 3 years since the last Environmental Response V Symposium. In the intervening period, we have seen many interesting developments in the KEAP1–NRF2 field. The purpose of the symposium is to exchange and discuss the most recent cutting–edge research in the field of KEAP1 and NRF2.


International Symposium: The Environmental Response Ⅵ
(November 3, 2023 – November 5, 2023)

Public Lecture: Space & Health
(November 5, 2023)


Masayuki Yamamoto
(Executive Director / Professor, Tohoku Medical Megabank Organization, Tohoku University)

Antonio Cuadrado
(Professor, Biochemistry and Molecular Biology, Autonomous University of Madrid)

Ken Itoh
(Professor, Hirosaki University)

Thomas W. Kensler
(Professor, Public Health Sciences, Fred Hutchinson Cancer Center)

Anna–Liisa Levonen
(Professor, Health Sciences, University of Eastern Finland)

Dai Shiba
(Manager for Rodent Research, Japan Aerospace Exploration Agency)


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Co–sponsored by

Supported by

  • Tohoku University Tohoku Medical Megabank Organization (ToMMo)
  • Innovations in Next-Generation Medicine (INGEM)
  • Kagome Co., Ltd.
  • Japan Aerospace Exploration Agency (JAXA)
  • Sendai Astronomical Observatory